| Customization: | Available |
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| CAS No.: | 4621-66-3 |
| Formula: | C6h6n2s |
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| Product name | Thionicotinamide |
| Synonyms | pyridine-3-carbothioamide; 3-Pyridinecarbothioamide; Pyridine-3-carbothioic acid amide |
| CAS No. | 4621-66-3 |
| Chemical Formula | C6H6N2S |
| EINECS | 225-036-6 |
| Molecular Weight | 138.19 |
| Item | Specification |
| Appearance | Yellow crystalline powder |
| Assay | ≥98.00% |
| Water | ≤0.50% |
| Melting point | 185-190ºC |
1kg bag
Medical Field
1)Treatment of Vitamin B1 Deficiency
It is essential for the normal operation of the nervous system. Thiamine is involved in the synthesis of neurotransmitters and the maintenance of nerve cell membranes. Thionicotinamide can relieve nervous - system - related symptoms caused by thiamine deficiency, such as numbness, tingling, and muscle weakness in the hands and feet.
Thionicotinamide is a derivative of Vitamin B1 (thiamine). Thiamine plays a crucial role in the body's carbohydrate metabolism. When the human body is deficient in thiamine, such as in the case of beriberi (symptoms include weakness, nerve damage, and heart problems, etc.), thionicotinamide can supplement the body's need for thiamine. For example, it helps in the process of converting carbohydrates into energy, especially in the step where pyruvate is decarboxylated and converted into acetyl - coenzyme A. The enzymatic reaction in this step requires thiamine pyrophosphate (TPP) as a co - enzyme, and thionicotinamide can provide a similar function through a certain conversion process in the body.
2)Alleviation of Symptoms Related to Alcoholic Neuropathy
Chronic alcohol abuse can lead to a deficiency of thiamine in the body because alcohol interferes with the absorption and utilization of thiamine. Thionicotinamide can be used to treat the neuropathy symptoms caused by thiamine deficiency in alcohol - dependent individuals, such as pain, a burning sensation, and loss of coordination in the extremities. It can help repair damaged nerve tissues and promote nerve regeneration and functional recovery.
Cosmetics Field
Thionicotinamide can be added to some skin - care products. It has certain antioxidant properties, which can scavenge free radicals in the body, reduce the damage of free radicals to skin cells, and thus help to delay skin aging, such as reducing the formation of wrinkles and improving skin elasticity.
It can also regulate the sebum secretion of the skin and has a certain improvement effect on oily skin, keeping the skin fresh and reducing skin problems such as acne.
Scientific Research Field
As a Tool for Biochemical and Physiological Research
Scientists use thionicotinamide to study the thiamine metabolism mechanism. By observing the responses of cells and organisms to thionicotinamide, the complex pathways of thiamine absorption, conversion, and utilization can be understood in depth. For example, in cell - culture experiments, by changing the concentration of thionicotinamide in the culture medium and observing the changes in the activity of related enzymes and the production of metabolites in the cells, the details of the thiamine - related metabolic pathways can be revealed.
It can be used in cell - culture and animal - model studies to investigate the roles of thiamine - related compounds in various biological processes, such as energy production (multiple steps in the tricarboxylic acid cycle require thiamine - related co - enzymes to participate) and redox reactions. In the study of mitochondrial energy metabolism, thionicotinamide can serve as a regulator to help determine the specific action sites and methods of thiamine and its derivatives in the process of oxidative phosphorylation.
Q1: Could you offer sample?
A1: Yes,sample is available. We can send samples by couriers or air as client's requirements.
Q2: What is MOQ?
A2: It usually does not have MOQ requirement. We will offer the most cost-effective solution including price and delivery way according to purchasing quantities.
Q3: What is the delivery time?
A3: For non-hazardous,it usually has stock. It can be sent within 7 days. For hazardous chemical,it may be 1~2 weeks. If it is our regular product, the time will be earlier.
Q4: Can you provide relevant documents?
A4: Of course. Bill of loading,Commercial Invoice, Packing List, Origin of Certificate , insurance, COA and SDS are available. Besides, we can offer other documents Certificate of Fumigation, documents approved by CCPIT or Consulate,etc.
Q5: Do you accept third party inspection?
A5: Yes,we do.
Q6: What is your payment term?
A6: TT,LC,Paypal,Western Union, ACH wire are available.
Q7: Is DDU or DDP available?
A7: Yes.
Q8: Could you look for other products on China market and coload one container?
A8: Yes. We have warehouse support to accomplish this.
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